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Engineering 'hairpins' increases CRISPR accuracy

Biomedical engineers have developed a method for improving the accuracy of the CRISPR genome editing technology by an average of 50-fold. The approach adds a short tail to the guide RNA that folds back and binds onto itself, creating a 'lock' that can only be undone by the targeted DNA sequence.

from Top Technology News -- ScienceDaily https://www.sciencedaily.com/releases/2019/04/190415113810.htm
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