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CRISPR-based 'allelic drive' allows genetic editing with selective precision and broad implications

Scientists developed a new version of a gene drive that allows the spread of specific, favorable genetic variants, also known as 'alleles,' throughout a population. The new 'allelic drive' is equipped with a guide RNA that directs CRISPR to cut undesired variants of a gene and replace it with a preferred version. Using a word processing analogy, CRISPR-based gene drives allow scientists to edit sentences of genetic information, while the new allelic drive offers letter-by-letter editing.

from All Top News -- ScienceDaily https://www.sciencedaily.com/releases/2019/04/190409172038.htm

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